The i2X – Intelligent Implementations of the European Electronic Health Record Exchange Format (EEHRxF) project is funded by the Digital Europe Programme. It kicked off officially on April 1, 2025. On the day of its launch, it made public its key activities. EHTEL is proud to have two EHTEL members who contribute to the project: Tic Salut Social and CHU Liège.
What is i2X
I2X stands for “A Common Electronic Health Record Format for Better Health Across Europe”. i2X is a flagship initiative that is involved in three key activities: it contributes to the goals of the Digital Europe Programme, aligns with the Single Digital Market strategy, and supports the ambitions of the Digital Decade 2030.
At the heart of i2X lies the European Electronic Health Record Exchange Format (EEHRxF) — the X-Format, a key component of the European Health Data Space Regulation which entered into force on 26 March 2025.
The X-Format is crucial for both the primary use of health data (supporting individual care) and secondary use (e.g., policy-making, research, and innovation). i2X will showcase how an “intelligent” implementation of the X-Format, supported by tailored IT solutions and positive user experiences among health professionals, can drive real change in European healthcare systems. I2X supports five data priority categories.
The project’s goal is to demonstrate sustainable, real-world adoption of the X-Format across all the data priority categories. More than 35 live demonstrators will run in 14 healthcare settings across 10 EU Member States. Thirty-eight partners are involved, and a growing number of others may join soon.
These in-service live demonstrators will prove that the EEHRxF can enhance health and care pathways without placing an additional burden on health professionals or systems. The project will generate practical insights and best practices that help accelerate adoption of the X-Format across Europe and promote interoperability among healthcare organisations and systems.
i2X is a hands-on implementation project, experimenting in real clinical environments to explore improved methods for capturing, exchanging, and using health data. i2X will deploy advanced digital tools that ease the everyday work of health professionals. As a result, the project will:
- Deliver evidence, policy recommendations, and technical guidance.
- Promote alignment with EU standards.
- Create opportunities for other organisations to join as early adopters.
The project plays a key role in advancing open innovation policies and in implementing MyHealth@EU services. Building on the foundations laid by other EU initiatives—such as Xt-EHR, XpanDH, and xShare - i2X will seek synergies with myHealth@myHands, another EU project which also launched on 1 April, 2025.
What are i2X’s commitments
i2X is deeply committed to improving experiences for both health professionals and patients, by optimising workflows and integrating cutting-edge technologies. It supports industry preparedness, offering a safe and structured space for X-Format adoption in clinical settings—primarily in public or publicly-oriented institutions. By bringing together numerous digital health companies, i2X fosters innovation and inclusiveness. It amplifies the voices of all key stakeholders, especially members of the overstretched health workforce.
As an ambitious, highly impactful initiative, i2X will tackle significant challenges, including interoperability gaps and resistance to digital transition.
The project will focus on demonstrating real-world benefits for patients and citizens, improving system efficiency, reducing costs, and providing actionable recommendations for successful EEHRxF implementation.
Who is involved in i2X
Over the next four years, 12 EU Member States will participate in i2X. They are Belgium, Cyprus, Czech Republic, Finland, France, Germany, Greece, Ireland, Italy, Portugal, the Netherlands and Spain. Most will develop demonstrators, some will integrate AI-based technologies. At least 1,200 healthcare professionals are expected to be engaged in the demonstrator sites. Ultimately, more than three million European citizens/patients will benefit from the project’s activities.
EHTEL is proud to be involved in i2X as an associate partner.
What are i2X’s expected impacts
- Up to 80% improvement in the availability of high-quality, structured health data in electronic health records—both nationally and cross-border.
- 75% increase in patients' access to their health data.
i2X represents a major step toward a unified digital health future for Europe. Structured, interoperable health data will empower citizens/patients, support professionals, and drive better health outcomes for all.